New Method for Detection of Heart Allograft Rejection
نویسندگان
چکیده
منابع مشابه
New method for detection of heart allograft rejection: validation of sensitivity and reliability in a rat heterotopic allograft model.
BACKGROUND Patients with inflammatory heart muscle diseases would benefit from a safe, convenient, rapidly performed diagnostic technique with real-time results not involving tissue removal. We have performed a detailed evaluation of detection of heart allograft rejection by autofluorescence in a heterotopic abdominal rat heart allograft model ex vivo. METHODS AND RESULTS Recipient rats with ...
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Background and Aims: Viroids are smallest known plant pathogens and cause several economically significant diseases. Until recently, viroid detection relied mainly on biological tests and indexing. Today various diagnostic techniques such as nucleic acid hybridization, southern blot and reverse transcription coupled with polymerase chain reaction (RT-PCR) are being used for detection and diag...
متن کاملSuppression of Allograft Rejection
Suppressor T cells (Ts) 1 have been described in many allogeneic systems and may play a role in preventing allograft rejection in tolerized (1-5), antigenpretreated (6-9), passively enhanced (10, 11), or cyclosporin A-treated (12, 13) recipients with long-term surviving transplants. The interactions between the Ts and their target cells are largely undefined. If Ts cells were specific for the a...
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BACKGROUND We evaluated a new marker of heart transplant rejection, the breath methylated alkane contour (BMAC). Rejection is accompanied by oxidative stress that degrades membrane polyunsaturated fatty acids, evolving alkanes and methylalkanes, which are excreted in the breath as volatile organic compounds (VOCs). METHODS Breath VOC samples (n = 1,061) were collected from 539 heart transplan...
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The cornea is avascular, enjoys relative immune privilege, and immunosuppressive treatment can be directly applied: yet data from all available reports indicate that allogeneic rejection is the commonest cause of corneal graft failure. In Australia, 5 year actuarial corneal graft survival is 72%: irreversible rejection accounts for at least 33% of all graft failures.' Graft survival is much sho...
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ژورنال
عنوان ژورنال: Circulation
سال: 1999
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.100.11.1236